Compatible with Adobe's CS? Specifically InDesign?

I don’t believe Spotlight finds text embedded within InDesign files. Will that mean DEVONsphere Express won’t be able to, either?

I’m going to guess that no, it won’t. DEVONthink won’t index them, so I expect Ds won’t.

That’s right, both DEVONthink and DEVONsphere require Spotlight support for third-party file formats.