Okay...So "create" button when creating new DB does nothing

New installation of DEVONthink Pro Office 2.10.1. On Osx 10.13.4

File>New Database>[location and name chosen]>[click create]…

Nothing happens.But the “Cancel” button works just fine.

You are likely trying to create a database in a cloud-synced location. This is specifically disallowed. The best option is a folder in your Home directory, like ~/Databases.