The same as @PaulAmosKreiner above - emptying the trash (that’s almost the only useful action after trashing ;-))
In my case I’m indexing my Downloads folder to process it from DT so I can directly review documents and put those needed into DT. Everything that’s not useful directly goes in the Trash. This prevents me from having to go through / review my Downloads folder separately (once in Finder to clean up documents, once in DT to decide where interesting documents need to go). Basicallly I’m managing my Downloads folder from DT which works well for me.
An aside: I have my extracted e-mail attachments in the same (ephemeral) database, which allows me to directly ignore any downloads which are actually downloaded e-mail attachments.