I reported this issue a while ago, and again during the beta process, but it still seems to be present in the release version of DTP. Basically, if you launch DTP on Mac OS X Server (10.6.2 here) the application launches, but you can’t access any menu items (all are grayed out), nor can you open a database or use the app.
I’ve tried deleting all of the DTP support files and preferences and reinstalling from scratch but the issue remains. I took a sample of DTP just after launching, and it’s available here:
Happy to provide more troubleshooting information as needed.
Neil