I posted my backup strategy here a while back.
Being “an idiot” is desperately easy - we’ve all been there, some more recently, some eons ago. A good (that is multiple cycles, multiple type, multiple location, multiple times daily) backup strategy will be a step towards insuring yourself against mistakes. Taking your time (yeah, I know…) is another. And testing is one more.
I use 150 dpi and have “Compress PDF” activated. I admit that I’m not completely happy with that setting - and the results change a little bit every time DT deploys a new version of the ABBYY software. Even so, for me it is a good enough compromise between usability, readability and storage space. As an aside, however, almost all my PDFs come directly from my scanner.