When should …
DisableFileCoordination: DEVONthink no longer uses file coordination, registering its interest in certain files and waiting for replies. This can cause very long delays if the coordinating process isn’t responding quickly.
… be used?
I wouldn’t use it unless you’re indexing large amounts of cloud-synced data and seeing stalls when navigating through the database. But @cgrunenberg can also respond with more authority than I on this.
Only if you should experience frequent stalls. But a sample would be useful first to figure out what’s actually going on, thanks.