DTPO 2.10.1 Will Not Load

I have not used this software since 2018. No matter what I do this software crashes every time I try to start it up. Can I download the software again?

Yes and you should. 2.10.1 is very out of date.

Download a new installer from here and replace your current version: Legacy Downloads

Do not run a third-party uninstaller. If your browser isn’t set to open safe downloaded files, just double-click the ZIP file to decompress it. Then double-click the disk image to open it, and drag and drop the application into the /Applications folder, allowing it to overwrite the old version when you’re prompted.
(There is no danger to your data when you do this. (1) Your data is not stored in the application, and (2) we would not give you instructions that would jeopardize your data.)

Also, if you are running macOS 10.15 Catalina now, you should read this: