Yes, there is a universe of knowledge, and that’s wonderful, though quite fuzzy.
But knowledge progresses through focus. That’s why we talk about scientific and academic disciplines. Disciplines are subsets of the universe of knowledge, built upon paradigms of definable relationships, as opposed to mere associations.
Think of biology as a cluster of galaxies, rather than the entire universe. It focuses on living organisms and includes sub disciplines from taxonomy to ecology, molecular biology and genetics. Information and methodologies from disciplines such as chemistry, physics, economics and others often play a role in research and understanding of biological studies. Like the universe as a whole (which includes living organisms and their behaviors as well as stars and asteroids), biology is a huge body of knowledge. But is has progressed by focus on many discrete areas such as how genes control production of proteins.
That leads me to discussion about why I favor creation of purpose-driven databases when using DEVONthink Pro or Pro Office, which allow multiple databases.
Unlike the Finder and most other document databases, DEVONthink includes artificial intelligence algorithms at the kernel of a database. And DEVONthink builds a Concordance of all the terms and their frequencies in the content of a database and “knows” where these terms exist in each document. These features support AI assistants in DEVONthink such as Classify (which looks at the patterns of contextual relationships of terms in the contents of groups in the database and can suggest appropriate filing location(s) for a new document) and See Also (which compares the contextual relationships of the terms used in a selected document and suggests other documents that may be contextually similar).
My main research database reflects my many decades of interest and work on environmental issues. It includes references from scientific and engineering disciplines, case histories of environmental problems, policy issues and laws and regulations. It’s large – about the word count of the Encyclopedia Brittanica – and sprawling in content, although all the content is related to my overall focus.
Most of the groups in this database have a pretty tight topical focus, which means that their contents do have distinctive patterns of contextual relationships so that Classify usually gives good recommendations for filing new content among hundreds of groups.
When I’m working on a project in this database I often use See Also to look for ideas. The suggestions I value most are those I wouldn’t have though of. An example I often cite is when I was reading a paper about the effects of invasive species on native populations in an ecological setting. See Also suggested a paper about the factors that affect chemical reaction equilibria. Although most of the terms were different in these two papers, DEVONthink had recognized the similarity of the quantitative principles that were in play. That suggestion improved my insight into the matter.
That database can run well for a time on a MacBook Air with 4 GB RAB. But as Apple’s memory management isn’t perfect, eventually memory will become clogged with “crud” inactive memory and the computer will slow down unless Restarted. On my MacBook Pro with 16 GB RAM I can have several other databases open, and work for a much longer time before a slowdown might occur. In practice, because I use a memory purge utility, I never see slowdowns on the MacBook Pro. But I would, were I to include all the databases I have at the same time.
I recommend multiple databases that are designed to meet a particular need or interest both to improve focus of work and allow better use of a Mac’s memory resources.
Of course, as my databases provide indexes to Spotlight, I can search across all my databases (open or closed) using Spotlight. But I rarely need to do that, as I know which database is most likely to contain what I’m looking for.