Great! I use a little application (Formulate Pro) to annotate PDFs with digital pen input, e.g., signing and initialing contract provisions, etc. (An example of neat things I can do with my ModBook, a custom Mac tablet computer.)
I’ve been negotiating a series of renovation projects with my contractor. He sends me a proposed contract for a project, I mark it up with changes, fire it back by email and he sends me back the revised proposal. Inevitably, some projects get modified by mutual agreement in mid-course.
The revised script lets me print as PDF directly (instead of in two steps) from Formulate Pro to a DT Pro database. I’ve got a database of all my renovation projects, including notes, correspondence and contract development for each, scanned checks, etc.
When I bought my log cabin, I first had it inspected for any problems. Parts of it date back 109 years, other parts are less than 10 years old. My renovation projects have to deal with necessary maintenance as well as changes for my own convenience. When I bought the cabin, I made up a list of project goals and an estimated cost for them. My database helps me keep track of progress and is extremely useful for planning and budgeting. I’m pleased that the actual costs of projects to date have been less than my original projections, and that the results have exceeded my expectations. But there will continue to be ongoing projects, some unexpected.
Eric, next time you and the family visit we won’t run out of water (I had to call a water truck to fill the cistern). Getting hooked up to the county water system took a year and a half longer than my original projections, but cost substantially less. And now I have a dishwasher installed! 
The cabin is rustic, but it’s got a lot of style and it’s comfortable. Central heat and air conditioning. My favorite room has lots of glass on three sides, looking out at the woods and wildlife, and a huge amount of shelving for my books. The outdoors is wonderful. I built a stairway up the hill to the new gazebo in the woods, and often work in the gazebo. Life is great!
Do I owe all this to DEVONthink? No, but it’s a big help. 
In fact, before I went shopping for a cabin here, I had built a database of likely candidates, with pictures, prices and other information garnered from Internet real estate sites, and including the one that I bought. That advance preparation made my shopping trip more efficient and effective.