Is there a way to create keyboard shortcuts to access groups, in particular the inbox?

Take a look at Script: Create or change smart group(s).

The script lets you edit the query and updates the Smart Group‘s name automatically if the query changed.

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great ! thank you very much

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Regarding Keyboard Maestro and which key to hit to complete action: This is how I do it:

Wait 0.1 seconds, then hit Command + Return.

Why don’t you just add the groups as Favorites then assign a hotkey to the item in the Go > Favorites menu? You can even open databases with this method.

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