You might want to read this thread from last year:
Where BLUEFROG links this blog post:
There is no separate setting for line spacing in the interface, but you can adjust the size of text in the item list (View Text Size) or the sidebars (Sidebar Text Size) in General Appearance. This also adjusts the spacing of elements a bit. Try to increase it.
If you tried that previously, it’s worth trying again, since the 3.9.7 release updated this a bit. From the release notes:
When setting a larger View Text Size via the General > Appearance preferences, the thumbnail icon scales better, the vertical alignment of some List view columns is more consistent, and better line spacing improves readability. This also applies to the Search and See Also & Classify inspectors.
For tags, you could try showing a Tags column and/or sort by tag.