New With Clipboard issue

I have an issue creating image records in DTPO using New With Clipboard. I am using SnapNDrag Pro to capture screenshots and have set the default file format to GIF, and chosen to automatically copy to the clipboard. The issue is that two slightly different workflows for getting the screenshots into DTPO give me different results in terms of file size. If I drag and drop from SnapNDrag into DTPO then I create a GIF file of a certain size, but if I create the file in DTPO by pasting using New from Clipboard then it results in a GIF file that is 10 times the size. I don’t see this inflation of file size if I paste the captured screenshot from the clipboard into Skitch or ImageWell. I’d appreciate any thoughts on this.