Open word documents indexed in DT leads to spinning wheel in DT

When I open a WORD-Document that is indexed in DEVONThink, this mostly results in the spinning wheel in the DT-window. This ends when I switch to the WORD-Document and click on the open document. After some time, the spinning wheel occurs again and I can use the same workaround. This only occurs with MS WORD (actual version 16.50, but occurred also in earlier versions) and in no other MS Office application or any other application. I work with DT3 Pro v.3.7.2 (problem also occurred in earlier versions) and macOS 11.4.

Welcome @gbackes

Where is the files indexed from - on a connected server, the local hard drive, …?