I have several programs that I keep my saved/working file directly in DEVONthink, open it from DEVONthink in whatever software it uses, then save when I’m done.
My question is; if I close DEVONthink before I finish working on and saving my file, will it still save in DEVONthink?
Some apps will save temporary versions of the working file, so keep an eye for it. If you at some point want to “Save As…” a copy, then save it to the desktop (that’s what I do) then drag it back into DT. That’s what I do. Occasionally I end up having multiple copies of a file, and I always have to make sure the most updated one is DT, and I open it form there.